Circulation MCQs set 3 for King Edward Medical University Entry Test Biology — 20 solved questions.
Q1. In a patient with a patent ductus arteriosus, which vessel is responsible for shunting blood from the aorta to the pulmonary artery?
Answer: Ductus arteriosus
Explanation: Ductus arteriosus shunts blood from aorta to pulmonary artery when patent; pulmonary vein is not directly involved.
Q2. Which structure is NOT a part of the conducting system of the heart?
Answer: Purkinje fibers of ventricular myocardium
Explanation: Purkinje fibers are part of the conducting system but the ventricular myocardium itself is not; it's the end pathway.
Q3. A person has a condition where the blood flows from the right atrium directly into the left atrium. Which congenital defect is most likely?
Answer: Atrial septal defect
Explanation: Atrial septal defect allows blood to flow between atria; patent foramen ovale is a related but distinct condition.
Q4. The hepatic portal vein is formed by the confluence of which two veins?
Answer: Superior mesenteric and splenic veins
Explanation: Hepatic portal vein is formed by superior mesenteric and splenic veins; inferior mesenteric drains into splenic.
Q5. In the hepatic sinusoids, which type of cell is responsible for phagocytosis?
Answer: Kupffer cells
Explanation: Kupffer cells are macrophages in hepatic sinusoids; hepatocytes are involved in metabolism, not phagocytosis.
Q6. Cardiac output is determined by which two factors?
Answer: Heart rate and stroke volume
Explanation: Cardiac output equals heart rate times stroke volume; blood pressure is a result, not a determinant.
Q7. The lymphatic system is characterized by which unique feature?
Answer: Presence of closed-ended lymphatic capillaries
Explanation: Lymphatic capillaries are closed-ended, allowing interstitial fluid entry; valves are present in larger lymphatics.
Q8. Which vessel has the highest oxygen content in a normal adult?
Answer: Pulmonary vein
Explanation: Pulmonary veins carry oxygenated blood from lungs to left atrium; aorta also carries oxygenated blood.
Q9. In a capillary, the rate of fluid filtration is determined by which factor?
Answer: All of the above pressures
Explanation: Fluid filtration is determined by balance of hydrostatic and oncotic pressures across capillary wall.
Q10. The coronary circulation receives its blood supply during which phase of the cardiac cycle?
Answer: Diastole
Explanation: Coronary circulation occurs mainly during diastole due to ventricular compression during systole.
Q11. Which of the following is a characteristic of the blood-brain barrier?
Answer: Tight junctions between endothelial cells
Explanation: Tight junctions between endothelial cells restrict passage across blood-brain barrier; fenestrated capillaries are elsewhere.
Q12. The foramen ovale is a shunt that allows blood to bypass which chamber in the fetal heart?
Answer: Lungs
Explanation: Foramen ovale allows blood to bypass lungs by shunting from right to left atrium in fetal circulation.
Q13. Which condition is associated with an abnormal connection between the aorta and the pulmonary artery?
Answer: Patent ductus arteriosus
Explanation: Patent ductus arteriosus is an abnormal connection between aorta and pulmonary artery.
Q14. The pressure in the left ventricle is highest during which phase?
Answer: Ventricular ejection
Explanation: Left ventricular pressure peaks during ventricular ejection; isovolumetric contraction precedes ejection.
Q15. Which factor increases venous return to the heart?
Answer: Muscle contraction
Explanation: Muscle contraction compresses veins and increases venous return; standing still decreases return.
Q16. Which part of the cardiac conduction system is responsible for the delay between atrial and ventricular contraction?
Answer: AV node
Explanation: AV node delays impulse to allow atrial contraction before ventricular contraction.
Q17. In which condition does the aorta arise from the right ventricle?
Answer: Transposition of the great arteries
Explanation: Transposition of great arteries involves aorta arising from right ventricle and pulmonary artery from left.
Q18. The hepatic artery and the hepatic portal vein supply blood to which organ?
Answer: Liver
Explanation: Hepatic artery and portal vein supply liver; hepatic artery brings oxygenated blood, portal vein brings nutrient-rich blood.
Q19. In the human heart, which structure separates the right atrium from the right ventricle?
Answer: Tricuspid valve
Explanation: Tricuspid valve separates right atrium from right ventricle; Mitral valve does the same for left side.
Q20. A patient's ECG shows a prolonged PR interval. Which process is being delayed?
Answer: AV node conduction
Explanation: PR interval represents time from SA node firing to ventricular depolarization; delay occurs in AV node.