During the resting membrane potential of a neuron, which ion's high permeability and outward leakage primarily maintain the internal negative charge?
Q1. During the resting membrane potential of a neuron, which ion's high permeability and outward leakage primarily maintain the internal negative charge?
Answer: Potassium ions
Explanation: Potassium ions leak out through non-gated channels to maintain negativity; sodium ions fail because their influx would cause depolarization instead.