A glucose molecule enters the cytosol to begin glycolysis and is immediately phosphorylated. Which enzyme is responsible for this initial activation step?
Q1. A glucose molecule enters the cytosol to begin glycolysis and is immediately phosphorylated. Which enzyme is responsible for this initial activation step?
Answer: Hexokinase
Explanation: Hexokinase catalyzes the first ATP-consuming step in glycolysis. Phosphofructokinase is tempting but it performs the second phosphorylation on fructose-6-phosphate.