A patient with sickle cell anemia has a single amino acid substitution in the hemoglobin chain. This primarily affects which level of protein organization?
Q1. A patient with sickle cell anemia has a single amino acid substitution in the hemoglobin chain. This primarily affects which level of protein organization?
Answer: Primary structure
Explanation: Sickle cell anemia results from a change in the primary sequence; secondary structure is tempting but refers to local folding patterns.