MDCAT Biology MCQ #737

Malonate acts as a potent inhibitor of succinate dehydrogenase. What is the mechanism by which malonate reduces the rate of this enzymatic reaction?

MDCAT Biology MCQ #737

  1. Question 1

    Q1. Malonate acts as a potent inhibitor of succinate dehydrogenase. What is the mechanism by which malonate reduces the rate of this enzymatic reaction?

    • A) Structural similarity to succinate
    • B) Irreversible binding to the allosteric site
    • C) Denaturation of the enzyme's tertiary structure
    • D) Covalent bonding to the catalytic site

    Answer: Structural similarity to succinate

    Explanation: Competitive inhibitors like malonate have structural similarity to the substrate, allowing them to block the active site. Non-competitive inhibitors bind elsewhere.