MDCAT Biology MCQ #743

Koshland proposed the Induced Fit Hypothesis in 1959. According to this mechanism, what happens when a substrate starts interacting with the enzyme?

MDCAT Biology MCQ #743

  1. Question 1

    Q1. Koshland proposed the Induced Fit Hypothesis in 1959. According to this mechanism, what happens when a substrate starts interacting with the enzyme?

    • A) The substrate changes shape to fit the enzyme
    • B) The enzyme remains rigid throughout the reaction
    • C) The active site undergoes a conformational change
    • D) The inhibitor binds to the allosteric site

    Answer: The active site undergoes a conformational change

    Explanation: Induced fit involves the enzyme changing shape to bind the substrate more effectively. This is a dynamic, not a rigid, process.