During the folding of a polypeptide into an alpha-helix, which mechanism stabilizes this specific secondary structure?
Q1. During the folding of a polypeptide into an alpha-helix, which mechanism stabilizes this specific secondary structure?
Answer: Hydrogen bonding between the backbone CO and NH groups
Explanation: Alpha-helices are stabilized by hydrogen bonds between the NH and CO groups of the polypeptide backbone, not the R-groups.