The industrial synthesis of salicylic acid, a precursor to aspirin, involves reacting sodium phenoxide with CO2. What is the standard temperature for this Kolbe’s reaction?
Q1. The industrial synthesis of salicylic acid, a precursor to aspirin, involves reacting sodium phenoxide with CO2. What is the standard temperature for this Kolbe’s reaction?
Answer: 120-150C
Explanation: Kolbe's reaction occurs at 120-150C and high pressure. 360C is the temperature for Dow's process, which is a common point of confusion.