A researcher wants to synthesize 4-phenylphenol from phenol. Which reagent is needed to introduce the second phenyl group?
Q1. A researcher wants to synthesize 4-phenylphenol from phenol. Which reagent is needed to introduce the second phenyl group?
Answer: Friedel-Crafts arylation
Explanation: Friedel-Crafts arylation fails due to the inability of aryl groups to be directly introduced via nucleophilic attack.