MDCAT Chemistry MCQ #351

The Cannizzaro reaction involves the disproportionation of Benzaldehyde. Which step in the mechanism is considered the slowest, rate-determining step?

MDCAT Chemistry MCQ #351

  1. Question 1

    Q1. The Cannizzaro reaction involves the disproportionation of Benzaldehyde. Which step in the mechanism is considered the slowest, rate-determining step?

    • A) Attack of OH- on the carbonyl carbon
    • B) Transfer of hydride ion to the second molecule
    • C) Protonation of the alkoxide intermediate
    • D) Deprotonation of the carboxylic acid formed

    Answer: Transfer of hydride ion to the second molecule

    Explanation: The rate-determining step in Cannizzaro is the transfer of a hydride ion. Nucleophilic attack is common but occurs faster than the hydride shift.