During the acid-catalyzed addition of ammonia derivatives to a ketone, what is the first step in the reaction mechanism?
Q1. During the acid-catalyzed addition of ammonia derivatives to a ketone, what is the first step in the reaction mechanism?
Answer: Protonation of carbonyl oxygen
Explanation: Acid-catalyzed reactions begin with protonation of the carbonyl oxygen, making the carbon more electrophilic. Option A describes base-catalyzed initiation.