MDCAT Chemistry MCQ #4895

Koshland proposed that the active site of an enzyme is flexible and adjusts its conformation upon substrate binding. This theory is the:

MDCAT Chemistry MCQ #4895

  1. Question 1

    Q1. Koshland proposed that the active site of an enzyme is flexible and adjusts its conformation upon substrate binding. This theory is the:

    • A) Lock and key model
    • B) Feedback inhibition
    • C) Competitive inhibition
    • D) Induced fit model

    Answer: Induced fit model

    Explanation: The induced fit model suggests the enzyme's active site changes shape to fit the substrate. Lock and key is tempting but implies rigidity.