MDCAT Chemistry MCQ #546

Which reaction of acetone involves the formation of an acyl anion?

MDCAT Chemistry MCQ #546

  1. Question 1

    Q1. Which reaction of acetone involves the formation of an acyl anion?

    • A) Reductive amination with ammonia
    • B) Electrophilic aromatic substitution with acetyl chloride
    • C) Base-catalyzed elimination to produce an alkene
    • D) Nucleophilic addition of hydroxide ion to produce an acyl anion

    Answer: Nucleophilic addition of hydroxide ion to produce an acyl anion

    Explanation: Nucleophilic addition of hydroxide ion involves the formation of an acyl anion. It fails because base-catalyzed elimination produces an alkene.