MDCAT Chemistry MCQ #569

During nucleophilic substitution, various species act as Lewis bases to attack the electrophilic carbon. Which of the following cannot act as a nucleophile?

MDCAT Chemistry MCQ #569

  1. Question 1

    Q1. During nucleophilic substitution, various species act as Lewis bases to attack the electrophilic carbon. Which of the following cannot act as a nucleophile?

    • A) NH3
    • B) OH-
    • C) CN-
    • D) H3O+

    Answer: H3O+

    Explanation: Nucleophiles are electron-rich species with lone pairs or negative charges. H3O+ is tempting but it is a cation and acts as an electrophile.