MDCAT Chemistry MCQ #572

Alkyl fluorides are remarkably stable and generally do not undergo nucleophilic substitution under standard conditions. What is the primary reason for this lack of reactivity?

MDCAT Chemistry MCQ #572

  1. Question 1

    Q1. Alkyl fluorides are remarkably stable and generally do not undergo nucleophilic substitution under standard conditions. What is the primary reason for this lack of reactivity?

    • A) It is the most polar bond
    • B) Fluorine is the smallest halogen
    • C) It has the lowest bond enthalpy
    • D) It has the highest bond enthalpy

    Answer: It has the highest bond enthalpy

    Explanation: RF is least reactive because the C-F bond is the strongest (467 kJ/mol). Polarity is tempting but bond strength determines reactivity here.