MDCAT Chemistry MCQ #582

To favor the E2 elimination mechanism over SN2 substitution for 2-bromopropane, which specific experimental modification should a chemist prioritize?

MDCAT Chemistry MCQ #582

  1. Question 1

    Q1. To favor the E2 elimination mechanism over SN2 substitution for 2-bromopropane, which specific experimental modification should a chemist prioritize?

    • A) Lowering the temperature to 0 degrees Celsius
    • B) Using a dilute aqueous solution of KOH
    • C) Increasing the temperature and using alcoholic KOH
    • D) Using a primary alkyl halide instead of tertiary

    Answer: Increasing the temperature and using alcoholic KOH

    Explanation: Elimination is favored over substitution at higher temperatures due to higher activation energy and increased entropy in E2 mechanisms.