MDCAT Chemistry MCQ #632

In the reaction of an alkyl halide, how does the nucleophilic strength of OH- compare to H2O regarding the reaction mechanism?

MDCAT Chemistry MCQ #632

  1. Question 1

    Q1. In the reaction of an alkyl halide, how does the nucleophilic strength of OH- compare to H2O regarding the reaction mechanism?

    • A) H2O is a stronger nucleophile than OH- ion.
    • B) OH- is a stronger nucleophile and favors SN2 mechanism.
    • C) Both nucleophiles are equal in strength for alkyl halides.
    • D) H2O favors SN2 because it is smaller than OH- ion.

    Answer: OH- is a stronger nucleophile and favors SN2 mechanism.

    Explanation: Strong, negatively charged nucleophiles like OH- favor SN2, whereas weak, neutral nucleophiles like H2O favor the SN1 mechanism.